Journal
EVOLUTIONARY APPLICATIONS
Volume 11, Issue 6, Pages 836-844Publisher
WILEY
DOI: 10.1111/eva.12608
Keywords
cancer resistance; ecotoxicology; experimental evolution; pollution; wildlife
Categories
Funding
- ANR (Blanc project EVOCAN)
- CNRS (INEE)
- Montpellier Herault Sport Club
- International Associated Laboratory Project France/Australia and Andre HOFFMANN (Fondation MAVA)
Ask authors/readers for more resources
Both field and experimental evolution studies have demonstrated that organisms naturally or artificially exposed to environmental oncogenic factors can, sometimes rapidly, evolve specific adaptations to cope with pollutants and their adverse effects on fitness. Although numerous pollutants are mutagenic and carcinogenic, little attention has been given to exploring the extent to which adaptations displayed by organisms living in oncogenic environments could inspire novel cancer treatments, through mimicking the processes allowing these organisms to prevent or limit malignant progression. Building on a substantial knowledge base from the literature, we here present and discuss this progressive and promising research direction, advocating closer collaboration between the fields of medicine, ecology, and evolution in the war against cancer.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available