Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2018, Issue 33, Pages 4571-4576Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201800912
Keywords
Nitration; Azidation; C-H activation; Copper
Categories
Funding
- National Natural Science Foundation of China [21472172, 21272212]
- Natural Science Foundation of Zhejiang Province [LY17B060009]
Ask authors/readers for more resources
A simple and facile protocols for copper-catalyzed regionselective C4 nitration and azidation of 1-naphthylamines via remote C-H activation that use of pyridyl amide fragment as the removable directing group have been firstly developed. These reactions proceed under mild conditions without any additives, tolerate a wide variety of functional groups, and afford a wide range of products in good to excellent yields. Control experiments suggest that those C-H activation reactions are likely to proceed through a single-electron-transfer (SET) process.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available