Journal
RSC ADVANCES
Volume 5, Issue 65, Pages 53073-53085Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra10561g
Keywords
-
Categories
Funding
- Department of Science and Technology [IFA12-CH-22]
- Alexander von Humboldt Foundation
Ask authors/readers for more resources
A selective palladium-catalysed arylation of 2,6-dibromopyridine has been developed by employing N-heterocyclic carbene ligands. Selective mono-arylation was performed in water/acetonitrile solvent system at ambient temperature with catalyst loading of 0.1 mol%. This reaction was also found to proceed smoothly in water although at a slightly elevated temperature of 80 degrees C. 2,6-Disubstituted and diversely substituted 2,6-pyridines were also obtained in high yields which will be of importance to organic and medicinal chemists.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available