Journal
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
Volume 61, Issue -, Pages 67-70Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.etap.2018.05.020
Keywords
Eco-pharmacovigilance; Pharmacovigilance; Pharmaceutical residues; Environment
Funding
- National Natural Science Foundation of China [81602108]
- Humanities and Social Science Foundation from Hubei province ministry of education [16Y023]
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Now, the occurrence of pharmaceuticals in natural environment has been frequently reported around the world. As a kind of biologically active compounds specially designed to be effective even at very low concentration levels, pharmaceuticals in the environment could have adverse impacts to the health of human beings or other non-targeted organisms due to long-term exposures. To minimize the pharmaceutical pollution from the perspective of drug administration, a new concept called as eco-pharmacovigilance (EPV) has been proposed as a kind of pharmacovigilance(PV) for the environment. However, as a new and comprehensive science, EPV has not sophisticated methods in practice and formalized implementation model up to now. Since EPV is a special kind of PV, it could be feasible to draw on the experience of PV as a possible and reasonable starting point for EPV. In this paper, we discussed the common methods and activities used in PV including spontaneous reporting, intensive monitoring, database studies, and their potential applicability to the environment. And we concluded that these common methods in PV could be adapted and applied to EPV. But there is still the need for organizational, technical and financial supports of the EPV system.
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