4.7 Article

Deltamethrin-induced nuclear erythrocyte alteration and damage to the gills and liver of Colossoma macropomum

Journal

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
Volume 25, Issue 15, Pages 15102-15110

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s11356-018-1622-1

Keywords

Acute toxicity; Genotoxicity; Histology; Pathology; Pyrethroid; Tambaqui

Funding

  1. CNPq (National Council of Scientific and Technological Development) [CNPq 305195/2016-6]

Ask authors/readers for more resources

Deltamethrin is one of the most commonly used pyrethroids in the world, and it has a high toxic potential, mainly on aquatic organism. Thus, the purpose of this study was to evaluate LC50 values of deltamethrin on tambaqui (Colossoma macropomum) fingerlings and to investigate genotoxic effects and histopathological responses. Fish were exposed to different concentrations of deltamethrin (0, 6.16 x 10(-3); 6.44 x 10(-2); 1.34 x 10(-1), and 1.93 x 10(-1) mg L-1) for 96 h. In addition, a genotoxicity analysis was carried out on peripheral blood erythrocytes and histopathological changes were classified by the severity degree of damage and organ functioning. The 96 h LC50 value for tambaqui was estimated at 5.56 x 10(-2) mg L-1 using a static test system. Nuclear abnormalities in exposed fish included micronuclei, blebbed, notched, 8-shaped, and binucleated nuclei forms. Deltamethrin significantly induced a notched nucleus compared to other abnormalities. A histopathological examination showed hepatic lesions and gill damage. Deltamethrin was found to be highly toxic; it induced genotoxicity and caused liver and gill inflammation in tambaqui.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available