4.7 Article

Genomic Assays for Identification of Chikungunya Virus in Blood Donors, Puerto Rico, 2014

Journal

EMERGING INFECTIOUS DISEASES
Volume 21, Issue 8, Pages 1409-1413

Publisher

CENTERS DISEASE CONTROL
DOI: 10.3201/eid2108.150458

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Funding

  1. Abbott Laboratories, Inc.
  2. National Institutes of Health (NIH) [R01-HL105704]
  3. Abbott Viral Discovery Award

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A newly developed transcription-mediated amplification assay was used to detect chikungunya virus infection in 3 of 557 asymptomatic donors (0.54%) from Puerto Rico during the 2014-2015 Caribbean epidemic. Viral detection was confirmed by using PCR, microarray, and next-generation sequencing. Molecular clock analysis dated the emergence of the Puerto Rico strains to early 2013.

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