Journal
WORLD JOURNAL OF RADIOLOGY
Volume 7, Issue 8, Pages 202-211Publisher
BAISHIDENG PUBLISHING GROUP INC
DOI: 10.4329/wjr.v7.i8.202
Keywords
Neoplasm metastasis; Radionuclide imaging; Magnetic resonance imaging; Computed tomography; Bone and bones
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Early detection of skeletal metastasis is critical for accurate staging and optimal treatment. This paper briefly reviews our current understanding of the biological mechanisms through which tumours metastasise to bone and describes the available imaging methods to diagnose bone metastasis and monitor response to treatment. Among the various imaging modalities currently available for imaging skeletal metastasis, hybrid techniques which fuse morphological and functional data are the most sensitive and specific, and positron emission tomography (PET)/computed tomography and PET/magnetic resonance imaging will almost certainly continue to evolve and become increasingly important in this regard.
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