Journal
ELECTRONIC JOURNAL OF BIOTECHNOLOGY
Volume 31, Issue -, Pages 24-33Publisher
UNIV CATOLICA DE VALPARAISO
DOI: 10.1016/j.ejbt.2017.10.012
Keywords
Antibiotic; Cholera; Gram-negative bacteria; Phage therapy; Vibrio anguillarum; Vibrio cholerae; Vibrio harveyi; Vibrio parahaemolyticus; Vibrio; Virulence
Categories
Funding
- Fondecyt [11140412, 11140257]
- Proyecto PUCV DI Investigacion Innovadora Interdisciplinaria [039.461/2017]
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Vibrios are common inhabitants of marine and estuarine environments. Some of them can be pathogenic to humans and/or marine animals using a broad repertory of virulence factors. Lately, several reports have indicated that the incidence of Vibrio infections in humans is rising and also in animals constitute a continuing threat for aquaculture. Moreover, the continuous use of antibiotics has been accompanied by an emergence of antibiotic resistance in Vibrio species, implying a necessity for efficient treatments. One promising alternative that emerges is the use of lytic bacteriophages; however, there are some drawbacks that should be overcome to make phage therapy a widely accepted method. In this work, we discuss about the major pathogenic Vibrio species and the progress, benefits and disadvantages that have been detected during the experimental use of bacteriophages to their control. (C) 2017 Pontificia Universidad Catolica de Valparaiso. Production and hosting by Elsevier B.V. All rights reserved.
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