Journal
EJSO
Volume 44, Issue 9, Pages 1344-1353Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ejso.2018.05.030
Keywords
Colon cancer; Laparoscopic surgery; Open surgery; Effectiveness; Patient reported outcomes; Health service research
Funding
- Instituto de Salud Carlos III
- European Regional Development Funds-ERDF [PS09/00314, PS09/00910, PS09/00746, PS09/00805, PI09/90460, PI09/90490, PI09/90453, PI09/90441, PI09/90397]
- Department of Health of the Basque Country [2010111098]
- Department of Education, Language Policy and Culture of the Basque Government [IT-620-13]
- Research Committee of the Hospital Galdakao
- thematic networks-REDISSEC (Red de Investigacion en Servicios de Salud en Enfermedades Cronicas)-of the Institute de Salud Carlos III
Ask authors/readers for more resources
Objective: There is limited information on health service use or patient-reported outcomes when comparing the effectiveness of laparoscopic with that of open surgery. The aim was to compare the effectiveness of laparoscopic with that of open surgery up to 2 years after intervention in patients with colon cancer. Methods: Prospective cohort study of patients with colon cancer who underwent surgery (laparoscopic or open surgery) between June 2010 and December 2012, at 22 hospitals. Main outcomes of the study were mortality, complications, reoperation, readmission, and patient-reported outcome measures (PROMs), as measured using the Hospital Anxiety and Depression Scale, Duke-UNC, EuroQol-5D, and European Organisation for Research and Treatment of Cancer-Q30 and Q29 at baseline, and 30 days and 1 and 2 years after surgery. Multivariable multilevel logistic regression and generalized linear models were used in analyses after adjusting for specific propensity scores developed for each outcome and time point. Results: In the multivariable analysis, the complication rates up to 30 days (infectious, surgical, and medical) and 1 year (surgical), and readmission rate at 30 days and at 2 years were higher among patients who underwent open surgery than among those who underwent laparoscopic surgery. There were no differences between the two surgical approaches in all other parameters assessed and in changes of all PROMs. Conclusions: Though in most outcomes both surgical approaches provide similar results up to 2 years after intervention, still the rates of some complications and readmission, mainly up to 30 days, are higher in open surgery. (C) 2018 Elsevier Ltd, BASO similar to The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available