Journal
DRUG DISCOVERY TODAY
Volume 23, Issue 5, Pages 960-973Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2017.11.003
Keywords
-
Categories
Funding
- ICAR, New Delhi, India
- UGC, New Delhi, India
- Jaswant Singh Gill Pharma Research Fellowship
Ask authors/readers for more resources
Galactosylated nanocarriers have recently emerged as viable and versatile tools to deliver drugs at an optimal rate specifically to their target tissues or cells, thus maximizing their therapeutic benefits while circumventing off target effects. The abundance of lectin receptors on cell surfaces makes the galactosylated carriers suitable for the targeted delivery of bioactives. Additionally, tethering of galactose (GAL) to various carriers, including micelles, liposomes, and nanoparticles (NPs), might also be appropriate for drug delivery. Here, we review recent advances in the development of galactosylated nanocarriers for active tumor targeting. We also provide a brief overview of the targeting mechanisms and cell receptor theory involved in the ligand-receptor-mediated delivery of drug carriers.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available