Journal
DRUG DELIVERY
Volume 25, Issue 1, Pages 766-772Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10717544.2018.1450910
Keywords
Hyaluronic acid; derivatives; drug carriers; drug delivery; tumor targeting
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Funding
- Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry
- Chongqing Key Research Project of Basic Science & Frontier Technology [cstc2017jcyjBX0012]
- Foundation Project of Chongqing Normal University [14XYY020]
- 14XYY020 [cstc2015jcyjA10054]
- Chongqing Normal University Postgraduate's Research and Innovation Project, China [YKC17004]
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Hyaluronic acid has good biocompatibility, biodegradability, and nonimmunogenicity. In addition, it has the ability to recognize specific receptors that are overexpressed on the surface of tumor cells, and cancer drugs can be targeted to the tumor cells to better kill them. Therefore, hyaluronic acid has attracted much attention as drug delivery vehicle. Herein, the application of hyaluronic acid as carrier in drug delivery was analyzed and summarized in detail. It showed that hyaluronic acid would have broad prospects for drug delivery.
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