Journal
DIGESTIVE AND LIVER DISEASE
Volume 50, Issue 1, Pages 1-5Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.dld.2017.10.025
Keywords
Exocrine pancreatic insufficiency; Gastrectomy; Pancreatic enzyme; Surgery
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Exocrine pancreatic insufficiency (EPI) is one of the possible mechanisms of fat maldigestion following gastric surgery, together with reduced food intake, loss of gastric reservoir, small bowel bacterial overgrowth and rapid small bowel transit. Oral pancreatic enzyme replacement therapy (PERT) is the mainstay of treatment for EPI. The efficacy and safety of pancreatic enzyme substitution in patients following gastric resection remains unclear. This review article summarizes relevant studies addressing PERT after gastric resection. (c) 2017 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
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