Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 46, Issue -, Pages 56-62Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2018.04.002
Keywords
-
Categories
Funding
- Biotechnology and Biological Sciences Research Council [BB/P02114X/1]
- University of Manchester President's Award for Research Excellence
- National Natural Science Foundation of China [31471254, 31725002]
- Bureau of International Cooperation, Chinese Academy of Sciences [172644KYSB20170042]
- BBSRC [BB/M025640/1, BB/M005690/1, BB/P02114X/1, BB/M005690/2] Funding Source: UKRI
- EPSRC [EP/P017401/1] Funding Source: UKRI
Ask authors/readers for more resources
Since the first synthetic gene was synthesized in 1970s, the efficiency and the capacity of made-to-order DNA sequence synthesis has increased by several orders of magnitude. Advances in DNA synthesis and assembly over the past years has resulted in a steep drop in price for custom made DNA. Similar effects were observed in DNA sequencing technologies which underpin DNA-reading projects. Today, synthetic DNA sequences with more than 10 000 bps and turnaround times of a few weeks are commercially available. This enables researchers to perform large-scale projects to write synthetic chromosomes and characterize their functionalities in vivo. Synthetic genomics opens up new paradigms to study the genome fundamentals and engineer novel biological functions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
