Journal
CURRENT OPINION IN CHEMICAL BIOLOGY
Volume 45, Issue -, Pages 148-156Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.cbpa.2018.05.009
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Funding
- National Institutes of Health [R01-GM107630]
- GAANN Fellowship
- BEST IGERT program (National Science Foundation) [DGE-1144901]
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Bioluminescent probes are powerful tools for visualizing biology in live tissues and whole animals. Recent years have seen a surge in the number of new luciferases, luciferins, and related tools available for bioluminescence imaging. Many were crafted using classic methods of optical probe design and engineering. Here we highlight recent advances in bioluminescent tool discovery and development, along with applications of the probes in cells, tissues, and organisms. Collectively, these tools are improving in vivo imaging capabilities and bolstering new research directions.
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