Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 50, Issue -, Pages 72-78Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2018.01.008
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Funding
- US National Institutes of Health [DK102910]
- Hamilton O. Smith Award Fund
- Agency of Science, Technology and Research (Singapore)
- Japan Society for the Promotion of Science
- NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES [R01DK102910] Funding Source: NIH RePORTER
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The primary cilium is a cell surface projection from plasma membrane which transduces external stimuli to diverse signaling pathways. To function as an independent signaling organelle, the molecular composition of the ciliary membrane has to be distinct from that of the plasma membrane. Here, we review recent findings which have deepened our understanding of the unique yet dynamic phosphoinositide profile found in the primary cilia.
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