Journal
CURRENT OPINION IN BIOTECHNOLOGY
Volume 50, Issue -, Pages 65-71Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.copbio.2017.11.008
Keywords
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Funding
- National Science Foundation [CBET-1349663]
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The current global dependence on fossil fuels for both energy and chemical production has spurred concerns regarding long-term resource security and environmental detriments resulting from increased CO2 levels. Through the installation of exogenous metabolic pathways, engineered cyanobacteria strains can directly fix CO2 into industrially relevant chemicals currently produced from petroleum. This review highlights some of the studies that have successfully implemented photomixotrophic conditions to increase cyanobacterial chemical production. Supplementation with fixed carbon sources provides additional carbon building blocks and energy to enhance production and occasionally aid in growth. Photomixotrophic production has increased titers up to 5-fold over traditional autotrophic conditions, demonstrating promising applications for future commercialization.
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