Journal
CURRENT MEDICAL RESEARCH AND OPINION
Volume 34, Issue 5, Pages 911-921Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/03007995.2017.1421528
Keywords
Cancer; drug delivery; nanomedicines; nanotechnology; site specific
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Purpose: Cancer remains a significant cause of morbidity and mortality across the globe. A recent report suggests around 14.1 million new cases and 8.2 million cancer-related deaths, which are expected to reach 21.7 million and 13 million by 2030 worldwide, respectively. Materials and Methods: Because of highly complex mechanisms of cancer progression, it is important to explore and develop new innovative technologies which are more efficient compared with presently available treatment options. Results: Currently, chemotherapy, radiation and surgery are the most commonly used cancer treatment methods. In the last decade, nanomedicine emerged as an alternative treatment option that uses specific drug-delivery systems, improves efficacy of drugs and reduces detrimental side effects to normal tissues. Conclusion: In this review, we have summarized cancer nanomedicines (active and passive drug delivery) available in the market. We have also discussed other nanomedicines that are at different stages of clinical trials.
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