Journal
SCIENTIA PHARMACEUTICA
Volume 83, Issue 2, Pages 353-367Publisher
MDPI
DOI: 10.3797/scipharm.1410-10
Keywords
Panamanian plant extracts; HPLC-based activity profiling; Fungicide; Insecticide; Herbicide
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Funding
- European Commission
- SENACYT
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A library of 600 taxonomically diverse Panamanian plant extracts was screened for fungicidal, insecticidal, and herbicidal activities. A total of 19 active extracts were submitted to HPLC-based activity profiling, and extracts of Bocconia frutescens, Miconia affinis, Myrcia splendens, Combretum aff. laxum, and Erythroxylum macrophyllum were selected for the isolation of compounds. Chelerythrine (2), macarpine (3), dihydrosanguinarine (5), and arjunolic acid (8) showed moderate-to-good fungicidal activity. Myricetin-3-O-(6 ''-O-galloyl)-beta-galactopyranoside (13) showed moderate insecticidal activity, but no compound with herbicidal activity was identified.
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