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Border collies of the genome: domestication of an autonomous retrovirus-like transposon

Journal

CURRENT GENETICS
Volume 65, Issue 1, Pages 71-78

Publisher

SPRINGER
DOI: 10.1007/s00294-018-0857-1

Keywords

Retrovirus-like transposon; Retrotransposon; Ty1; Mediator; Domestication

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Retrotransposons often spread rapidly through eukaryotic genomes until they are neutralized by host-mediated silencing mechanisms, reduced by recombination and mutation, and lost or transformed into benevolent entities. But the Ty1 retrotransposon appears to have been domesticated to guard the genome of Saccharomyces cerevisiae.

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