4.8 Editorial Material

LPS Transport: Flipping Out over MsbA

Journal

CURRENT BIOLOGY
Volume 28, Issue 1, Pages R30-R33

Publisher

CELL PRESS
DOI: 10.1016/j.cub.2017.10.067

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Lipopolysaccharide synthesis and transport pathways are attractive targets for the development of new antimicrobial therapeutics. The ABC (ATP Binding Cassette) transporter MsbA has been recently described as employing a 'trap and flip' mechanism of lipopolysaccharide transport. This represents a novel mechanism amongst known lipid ABC transporters.

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