Journal
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION
Volume 28, Issue 2, Pages 139-154Publisher
BEGELL HOUSE INC
DOI: 10.1615/CritRevEukaryotGeneExpr.2018022258
Keywords
free radicals; antioxidants; reactive oxygen species; reactive nitrogen species
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The role of free radicals in various human ailments is well established. Still, the researchers continue to emphasize the involvement of free radicals in these disorders. Antioxidants are being used as an effective tool as a defense against disorders caused by free radicals. This review presents brief detail regarding the nature, types, and sources of free radicals that are of pharmacological interest. A summary of the antioxidants, along with possible mechanisms, has also been incorporated. The role of free radicals and antioxidants in various human disease are also presented.
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