4.6 Article

MnO2 catalyzed formylation of amines and transamidation of amides under solvent-free conditions

Journal

RSC ADVANCES
Volume 5, Issue 98, Pages 80441-80449

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra13094h

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Funding

  1. Council of Scientific and Industrial Research (CSIR), New Delhi, India

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A facile and efficient MnO2 catalyzed one-pot protocol for formylation of amine and transamidation of primary and secondary amides by amines has been developed. The present methodology is operationally simple, inexpensive and scalable under solvent free conditions. A series of formylated and transamidated products were synthesized in good to excellent yields.

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