Journal
AIDS AND BEHAVIOR
Volume 19, Issue 11, Pages 2049-2056Publisher
SPRINGER/PLENUM PUBLISHERS
DOI: 10.1007/s10461-015-1064-4
Keywords
Panic symptoms; Psychiatric disorder; Medication adherence; Antiretroviral therapy use; Viral suppression
Funding
- National Heart, Blood, and Lung Institute [5T32-HL-007180]
- National Institute of Alcohol Abuse and Alcoholism [R01 AA16893, R01 AA14500, U24AA020801, U01AA0120793]
- National Institute of Drug Abuse [R01 DA11602]
- Johns Hopkins Center for AIDS Research [P30 AI094189]
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Panic symptoms are prevalent among PLWHAs, yet few studies have examined their relationship with HIV outcomes. Using data from an observational cohort study in Baltimore, MD, we examined the association between panic symptoms and antiretroviral therapy (ART) use, medication adherence, and viral suppression. Data were analyzed using generalized estimating equations and adjusted for age, sex, race/ethnicity, cocaine and/or heroin use, clinic enrollment time, alcohol use, and depressive symptoms. Between June 2010 and September 2012, 1195 individuals participated in 2080 audio computer assisted interviews; 9.9 % (n = 118) of individuals endorsed current panic symptoms. In multivariate analysis, panic symptoms were associated with decreased ART use (IRR 0.94; p = 0.05). Panic symptoms were neither associated with medication adherence nor viral suppression. These findings were independent of depressive symptoms and substance use. Panic symptoms are under-recognized in primary care settings and present an important barrier to ART use. Further studies investigating the reasons for this association are needed.
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