Journal
RESPIRATORY INVESTIGATION
Volume 53, Issue 6, Pages 249-258Publisher
ELSEVIER
DOI: 10.1016/j.resinv.2015.02.004
Keywords
COPD; Comorbidities; Disease prevalence; Disease management
Categories
Funding
- Priority Research Centre for Asthma and Respiratory Diseases Ph.D. Scholarship
- Emlyn and Jennie Thomas Postgraduate Medical Research Scholarship through the Hunter Medical Research Institute [G1401393]
- Boehringer Ingelheim Chronic Obstructive Pulmonary Disease Research Fellowship through the Lung Foundation Australia [G1300813]
- NHMRC practitioner fellowship [G1300083]
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Patients with chronic obstructive pulmonary diseases (COPD) often experience comorbid conditions. The most common comorbidities that have been associated with COPD include cardiovascular diseases, lung cancer, metabolic disorder, osteoporosis, anxiety and depression, skeletal muscle dysfunction, cachexia, gastrointestinal diseases, and other respiratory conditions. Not only are comorbidities common but they also considerably influence disease prognosis and patients' health status, and are associated with poor clinical outcomes. However, perusal of literature indicates that little has been done so far to effectively assess, manage, and treat comorbidities in patients with COPD. The aim of this review is to comprehensively narrate the comorbid conditions that often coexist with COPD, along with their reported prevalence and their significant impacts in the disease management of COPD. A perspective on integrated disease management approaches for COPD is also discussed. (C) 2015 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.
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