Journal
FOOD RESEARCH INTERNATIONAL
Volume 77, Issue -, Pages 156-161Publisher
ELSEVIER
DOI: 10.1016/j.foodres.2015.07.024
Keywords
Spent coffee; Bioaccessibility; Permeability; Antioxidant activity; In vitro gastrointestinal digestion, in vitro colonic fermentation
Categories
Funding
- Consejo Nacional de Ciencia y Tecnologia (CONACYT) [206398]
Ask authors/readers for more resources
Spent coffee, a waste produced after beverage preparation, contains large amounts of several human health related compounds. The bioaccessibility, permeability and antioxidant activity of phenolic compounds from spent coffee (medium and dark-roasted) were evaluated using an in vitro gastrointestinal assay, intestinal absorption and colonic fermentation of non-digestible spent coffee fraction. Digested samples displayed lower amounts of phenolic compounds and flavonoids, but higher antioxidant activity (1-8 folds) compared to their respective non-digested (undigested) controls due to high release of condensed tannins at the colonic stage. SC polyphenols released during simulated GI digestion scavenged free radicals and these antioxidants increased during the transition from acidic to alkaline environment rapidly permeating through the small intestine by passive diffusion. Our results highlight the in vivo potential physiological role of SC phenolic compounds to scavenge free radicals present in the systemic circulation and target tissues, suggesting their potential health benefits and justifying their value addition. Further studies are needed to elucidate the clinical implication of these findings in human subjects. (C) 2015 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available