Journal
METABOLITES
Volume 5, Issue 4, Pages 733-765Publisher
MDPI
DOI: 10.3390/metabo5040733
Keywords
cardiovascular disease; diabetes; food bioactives; functional food; resistant starch; polyphenols; cyclo (His-Pro)
Categories
Funding
- Human Nutrition Research Fund, State of Texas
- Freeman Heart Association Endowment in Cardiovascular Diseases
Ask authors/readers for more resources
There has been an unprecedented worldwide rise in non-communicable metabolic diseases (NCDs), particularly cardiovascular diseases (CVD) and diabetes. While modern pharmacotherapy has decreased the mortality in the existing population, it has failed to stem the rise. Furthermore, a large segment of the world population cannot afford expensive pharmacotherapy. Therefore, there is an urgent need for inexpensive preventive measures to control the rise in CVD and diabetes and associated co-morbidities. The purpose of this review is to explore the role of food bioactives in prevention of NCDs. To this end, we have critically analyzed the possible utility of three classes of food bioactives: (a) resistant starch, a metabolically resistant carbohydrate known to favorably modulate insulin secretion and glucose metabolism; (b) cyclo (His-Pro), a food-derived cyclic dipeptides; and (c) polyphenol-rich berries. Finally, we have also briefly outlined the strategies needed to prepare these food-bioactives for human use.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available