Journal
CURRENT OBESITY REPORTS
Volume 4, Issue 4, Pages 429-440Publisher
SPRINGER
DOI: 10.1007/s13679-015-0176-5
Keywords
Obesity; Adipose tissue; Vitamin D; Insulin resistance; Inflammation; Review
Categories
Ask authors/readers for more resources
Obese subjects are often characterized by low plasma 25-hydroxy-vitamin D (25OHD) levels. Many explanations for this association have been proposed. Low plasma 25OHD is associated with obesity-related comorbidities such as insulin resistance, type 2 diabetes mellitus, and low-grade inflammation. In this review, we discuss the proposed mechanisms for low 25OHD in obesity and explore the results of recent RCTs on vitamin D (VD) supplementation on obesity and its metabolic complications such as insulin resistance and type 2 diabetes. Although the results from these clinical randomized controlled trials vary, the general picture is that VD treatment of obese individuals does not seem to be an effective treatment of obesity-related metabolic complications.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available