Journal
CLINICAL CASE REPORTS
Volume 3, Issue 11, Pages 942-944Publisher
WILEY
DOI: 10.1002/ccr3.399
Keywords
Anti-Pr; cold autoimmune hemolytic anemia; eculizumab; rituximab
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Key Clinical Message Severe cold agglutinin disease with hemodynamic compromise requires rapid stabilization of the autoimmune hemolytic anemia as a bridge to the immunosuppressive effect of rituximab. Herein, we describe eculizumab treatment of severe complement-mediated hemolysis in a patient whose hemodynamic status deteriorated in spite of supportive blood transfusions and therapeutic plasma exchange.
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