Journal
CLINICS IN PERINATOLOGY
Volume 45, Issue 2, Pages 257-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.clp.2018.01.011
Keywords
Continuous positive airway pressure; Bronchopulmonary dysplasia; Ventilatory-induced lung injury; Sustained lung inflation; INSURE; Randomized controlled trial; Mechanical ventilation; Infant flow driver
Categories
Funding
- Fisher Paykel
- NATIONAL HEART, LUNG, AND BLOOD INSTITUTE [K08HL098562, R01HL132941] Funding Source: NIH RePORTER
Ask authors/readers for more resources
Routine use of continuous positive airway pressure (CPAP) to support pre term infants with respiratory distress is an evidenced-based strategy to decrease the incidence of bronchopulmonary dysplasia. However, rates of CPAP failure remain unacceptably high in very premature neonates, who are at high risk for developing bronchopulmonary dysplasia. Using the GRADE framework to assess the quality of available evidence, this article reviews strategies aimed at decreasing CPAP failure, starting with delivery room interventions and followed through to system-based efforts in the neonatal intensive care unit. Despite best efforts, some very premature neonates fail CPAP. Also reviewed are predictors of CPAP failure in this vulnerable population.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available