Journal
CLINICAL SCIENCE
Volume 132, Issue 8, Pages 851-868Publisher
PORTLAND PRESS LTD
DOI: 10.1042/CS20171620
Keywords
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Categories
Funding
- ARUK, ARUK Scotland network
- Alzheimer's Society
- BHF
- BHF Cardiovascular centre
- MRC-DPUK
- Royal Society Edinburgh
- Stroke Association
- Fondation Leducq
- Academy of Medical Sciences (AMS) [SBF001\\1012] Funding Source: researchfish
- Alzheimers Research UK [ART-PG2010-3, ARUK-NAS2016B-1, ARUK-IRG2014-10, ARUK-PhD2013-18, ARUK-PhD2015-15, ARUK-PG2015-11, ARUK-2015DDI-OX, ARUK-NCG2013A-3, ARUK-SRF2013-4, ART-PG2011-1, ARUK-PG2013-22, ARUK-PPG2016A-3, ART-NCG2007A-2, ARUK-PG2016B-6] Funding Source: researchfish
- British Heart Foundation [PG/15/44/31574] Funding Source: researchfish
- Chief Scientist Office [CZB/4/517] Funding Source: researchfish
- Epilepsy Research UK [P1501] Funding Source: researchfish
- Lundbeck Foundation [R155-2016-552] Funding Source: researchfish
- Medical Research Council [UKDRI-4002, G1100540, G0900652, UKDRI-4005, G0500247, G0400074, MR/L023784/1, MC_PC_14095, MR/L003384/1, G0502157, MR/L023784/2, MR/K015397/1, MR/M013553/1, MR/K017047/1, MR/N003403/1, MR/K026992/1] Funding Source: researchfish
- National Institute for Health Research [NF-SI-0617-10150, NF-SI-0515-10044] Funding Source: researchfish
- Novo Nordisk Fonden [NNF13OC0004258] Funding Source: researchfish
- Rosetrees Trust [M507] Funding Source: researchfish
- Stroke Association [PPA2016/02, TSA2008/09, TSA15LECT05, PPA2016/01] Funding Source: researchfish
- MRC [MC_PC_14095, MR/L023784/2, MR/L023784/1, MR/M013553/1, G0500247, MR/L003384/1, MR/N003403/1, MR/R005567/1, MR/R014140/1, MR/K015397/1, G1100540, UKDRI-4002, UKDRI-4005, G0400074, G0502157, MR/K017047/1, G0900652] Funding Source: UKRI
Ask authors/readers for more resources
Cerebral small vessel disease (SVD) is a major contributor to stroke, cognitive impairment and dementia with limited therapeutic interventions. There is a critical need to provide mechanistic insight and improve translation between pre-clinical research and the clinic. A 2-day workshop was held which brought together experts from several disciplines in cerebrovascular disease, dementia and cardiovascular biology, to highlight current advances in these fields, explore synergies and scope for development. These proceedings provide a summary of key talks at the workshop with a particular focus on animal models of cerebral vascular disease and dementia, mechanisms and approaches to improve translation. The outcomes of discussion groups on related themes to identify the gaps in knowledge and requirements to advance knowledge are summarized.
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