Characteristics of computed tomography perfusion parameters in non-small cell-lung-cancer and its relationship to histology, size, stage an treatment response

Objectives: To analyze computed tomography perfusion (CTP) parameters in NSCLC. Materials and methods: Prospective study, 152 patients with NSCLC. CTP parameters were correlated with histology, stage, size and response to conventional chemotherapy/radiotherapy. Results: Neuroendocrine tumours presented higher BV (p 0.002). Negative correlation of PMB (p 0.003) and positive of MTT (p 0.046) with T stage was found. BF showed negative correlation with size. No differences were found with the RECIST levels of response to chemotherapy/radiotherapy. Conclusions: CTP parameters were highly variable. Neuroendocrine tumours presented higher BV and PMB values. Perfusion parameters do not differ depending on the stage and do not predict response to treatment.