4.5 Article

Five-year visual outcome among people with correctable visual impairment: the Liwan Eye Study

Journal

CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
Volume 46, Issue 5, Pages 462-467

Publisher

WILEY
DOI: 10.1111/ceo.13127

Keywords

correctable visual impairment; longitudinal cohort study; non-correctable visual impairment

Categories

Funding

  1. Fundamental Research Funds of the State Key Laboratory in Ophthalmology, National Natural Science Foundation of China [81420108008, 81570843 H1204]
  2. Science and Technology Planning Project of Guangdong Province, China [2013B20400003]
  3. University of Melbourne at Research Accelerator Program
  4. CERA Foundation

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ImportanceLongitudinal data on visual outcome of correctable visual impairments (VI) are of paramount importance for decision-maker to estimate burden and demand to treat avoidable VI. BackgroundTo assess the 5-year visual outcome among participants with correctable VI and to identify associated risk factors. DesignPopulation-based longitudinal cohort study. ParticipantsParticipants with correctable VI at baseline attended the 5-year follow-up visit of the Liwan Eye Study. MethodsPresenting visual acuity (PVA) with habitual refractive correction was assessed using an Early Treatment Diabetic Retinopathy Study (ETDRS) chart. Then participants with PVA <6/12 in either eye underwent further non-cycloplegic subjective refraction to obtain their best-corrected visual acuity. Correctable VI was defined as having a PVA of <6/12 in the better eye which could be improved to 6/12 after refractive correction. Main Outcome MeasuresThe 5-year visual outcome among participants with correctable VI. ResultsAmong 1405 participants at baseline examination, 188 (13.4%) had correctable VI, of whom 118 (62.8%) were re-examined at the 5-year follow-up, including 39 (33.9%) who progressed to non-correctable VI, 43 (37.4%) who had persistent correctable VI and 33 (28.7%) who were converted to normal vision. In multivariate logistic regression, compared with participants who were no longer visual impaired, significant risk factors for participants with persistent VI were older, had income <1000RMB/month, and more myopia spherical equivalent. Conclusions and RelevanceOver two of three participants with correctable VI remained to have VI after 5 years, among whom 50% are correctable by spectacles, highlighting the need to improve the refractive care accessibility to treat avoidable VI in China.

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