Process optimization of microencapsulation of curcumin in γ-polyglutamic acid using response surface methodology

The aim of this study was to develop an optimal microencapsulation method for an oil-soluble component (curcumin) using gamma-PGA. The results show that Span80 significantly enhances the encapsulation efficiency (EE) of gamma-Na+-PGA microcapsules. Therefore, the effects of gamma-Na+-PGA, curcumin and Span80 concentration on EE of gamma-Na+-PGA microcapsules were studied by means of response surface methodology (RSM). It was found that the optimal microencapsulation process is achieved by using gamma-Na+-PGA 6.05%, curcumin 15.97% and Span80 0.61% with a high EE% (74.47 +/- 0.20%). Furthermore, the models explain 98% of the variability in the responses. gamma-Na+-PGA seems to be a good carrier for the encapsulation of curcumin. In conclusion, this simple and versatile approach can potentially be applied to the microencapsulation of various oil-soluble components for food applications. (C) 2014 Elsevier Ltd. All rights reserved.