Journal
MEDICAL IMAGE COMPUTING AND COMPUTER-ASSISTED INTERVENTION, PT III
Volume 9351, Issue -, Pages 276-283Publisher
SPRINGER INTERNATIONAL PUBLISHING AG
DOI: 10.1007/978-3-319-24574-4_33
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Automated cell detection in histopathology images is a hard problem due to the large variance of cell shape and appearance. We show that cells can be detected reliably in images by predicting, for each pixel location, a monotonous function of the distance to the center of the closest cell. Cell centers can then be identified by extracting local extremums of the predicted values. This approach results in a very simple method, which is easy to implement. We show on two challenging microscopy image datasets that our approach outperforms state-of-the-art methods in terms of accuracy, reliability, and speed. We also introduce a new dataset that we will make publicly available.
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