Journal
CIRCULATION RESEARCH
Volume 122, Issue 3, Pages 399-401Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1161/CIRCRESAHA.117.312512
Keywords
adenosine; gene expression; inosine; mice; RNA editing
Funding
- V.V. Cooke Foundation
- University of Louisville School of Medicine
- EVPRI Internal Research Grant from the Office of the Executive Vice President for Research and Innovation at the University of Louisville
- Mansbach Family
- Gheens Foundation
- University of Louisville
- National Institutes of Health [R01 HL083320, R01 HL094419, HL131647, P20 GM103492, P01 HL078825]
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Increasing usage of next-generation sequencing technology will illuminate the extent of RNA modifications, which may affect various pathophysiological conditions. Here, we will highlight one such category of RNA modification called RNA editing, which can be detected from RNA sequencing data by simply modifying the data analysis pipeline using bioinformatics methods.
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