4.5 Article

Recent Advances in Organic Electrochemical C-H Functionalization

Journal

CHINESE JOURNAL OF CHEMISTRY
Volume 36, Issue 4, Pages 338-352

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cjoc.201700740

Keywords

organic electrochemistry; C-H functionalization; carbon-carbon bond formation; carbon-heteroatom bond formation

Funding

  1. Strategic Priority Research Program of the Chinese Academy of Sciences [XDB20000000]
  2. 1000-Youth Talents Plan
  3. NSF of China [21421091, 21572245, 21772222, 21772220]
  4. S&TCSM of Shanghai [15PJ1410200, 17JC1401200]

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Organic electrochemistry has a rich history in organic synthesis and has been considered as a promising alternative to traditional chemical oxidants and reductants because it obviates the use of stoichiometric amount of dangerous and toxic reagents. In particular, the electrochemical C-H bonds functionalization is one of the most desirable approaches for the construction of carbon-carbon (C-C) and carbon-heteroatom (C-X) bonds. This review summarizes the substantial progress made in the last few years in C-H functionalization via organic electrochemistry. It is divided into sections on C-C, C-N, C-O, C-S, C-Halogen and C-P bond formation.

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