A polarization method for quickly distinguishing the morphology of electro-spun ultrafine fibers

In the fields of tissue engineering and controlled drug release, electro-spun fibers are often required to have structural characteristics such as high porosity and large specific surface area. The traditional scanning electron microscope can observe the microscopic appearance of the sample clearly, but it damage to the polymer electro-spun fiber, and the detection takes a long time. In view of this, we have tested a polarization method to quickly distinguish different morphological features of the samples, such as smooth surface, microporous, and beaded microspheres using the depolarization parameter MMD-Delta, which is obtained by the Mueller matrix polar decomposition. The preliminary results show that this method is simple, fast, and potentially capable of non-destructive evaluation of the microstructure properties of the object surface. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.