Cucurbit[10]uril-based chemistry

Cucurbit[n]urils (CB[n]s, n = 5-8,10,13-15) have been proven to be an interesting macrocyclic family with their distinctive molecular recognition properties and fascinating applications in fields such as catalysis, supramolecular materials, drug delivery and biological systems. With the biggest cavity in the CB[n]s family, CB[101 shows its unique molecular recognition properties that are rather distinctive from other CB [h]s. In this review, we summarize the progresses in CB[10]-based chemistry since CB[10] was first reported as CB[10]center dot CB[51 complex in 2001. Purification, molecular recognition and supramolecular assembly of CBI[10] will be described and an outlook will be given for further exploration of CBI[10]-based chemistry. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.