Journal
CHEMOSPHERE
Volume 198, Issue -, Pages 216-225Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.chemosphere.2018.01.140
Keywords
Molybdenum disulfide; Nano-silver; Co-contamination; Ecotoxicity; Nanotoxicity; Metabonomics
Categories
Funding
- National Natural Science Foundation of China [21506096, 21776136, 21476111]
- National High Technology Research and Development Program of China [2013AA020302, 2014AA021703]
- Chief Specialist Program of Jiangsu Association for Science and Technology
- Program for Innovative Research Team in Universities of Jiangsu Province
- Top-notch Academic Programs Project of Jiangsu Higher Education Institutions, TAPP [PPZY2015B155]
- SICAM Scholarship
Ask authors/readers for more resources
As a new rising star in the post-graphene two-dimensional materials (2DMs), molybdenum disulfide (MoS2) attracts increasing attentions and is widely applied. However, the chemical and toxicological interaction between MoS2 and other co-contaminants is still poorly understood. Nano-silver (N-Ag) is the most commonly used nanomaterial in commercial products and distributed widely in the environment. Herein, we investigated the effects of chitosan functionalized MoS2 (CS-MoS2) nanosheets, a water-dispersible form of MoS2, on the microbial toxicity of N-Ag. We found that the incorporation of CS-MoS2 nanosheets attenuated the oxidative stress induced by N-Ag on yeast cells, while caused more membrane stress. In addition, the inhibition of N-Ag on the metabolic activities of yeast cells could be attenuated by CS-MoS2 nanosheets as well. The coexistence of N-Ag and CS-MoS2 nanosheets mainly perturbed the amino acid-related metabolic pathways in yeast cells, and phosphoric acid was a potential nanotoxicity biomarker. We further found that CS-MoS2 nanosheets dramatically absorbed the Ag ion released from N-Ag, which might be responsible for its attenuation effect on the microbial toxicity of N-Ag. Our findings provide more new insights for the ecotoxicity evaluation of MoS2 and other 2DMs. (C) 2018 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available