Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 24, Issue 41, Pages 10475-10487Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201801463
Keywords
anion transport; bicarbonate; chloride; nitrate; sulfate
Categories
Funding
- ARC [DP170100118, DP180100612, LE180100050]
- The University of Sydney
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The anion transport properties of a series of previously reported tren-based anionophores have been revisited using new assays designed to measure anion uniport. This study provides new insights into the transport mechanism and selectivity of this important class of transporters. Specifically, we report the chloride and nitrate transport selectivity of these systems and quantify sulfate transport to determine EC50 values for sulfate transport for the first time. Two new assays were developed to study bicarbonate transport allowing accurate quantification of chloride/bicarbonate exchange.
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