Journal
CHEMISTRY-A EUROPEAN JOURNAL
Volume 24, Issue 10, Pages 2375-2378Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201800019
Keywords
cycloadditions; cycloisomerization; macrocycles; polycyclic; transannular
Categories
Funding
- Research Grants Council of Hong Kong [GRF HKU 7016/12P]
- State Key Laboratory of Synthetic Chemistry
- University of Hong Kong
Ask authors/readers for more resources
Transannular [4+3] cycloadditions of dienophiles derived from macrocyclic epoxy ketones produce fused ring systems having central cycloheptane subunits. In some cases, the base directly induced cycloisomerization of the epoxy ketones to yield the cycloadducts; in others, the epoxy ketones were transformed into their corresponding enolsilanes before undergoing cycloaddition. Enantiomerically enriched tricyclic arrays were obtained from cycloadditions starting from optically pure epoxy ketones.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available