Journal
CHEMISTRY LETTERS
Volume 47, Issue 1, Pages 23-26Publisher
CHEMICAL SOC JAPAN
DOI: 10.1246/cl.170918
Keywords
Intracellular Mg2+ concentration; Red fluorescent turn-off probe; Ratiometric imaging
Categories
Funding
- MEXT, Japan [24651259, 25220207, 15H03120, 15H00818, 16K13102, 24104004, 16H00768]
- JSPS through its Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST Program)
- MHLW, Japan
- CREST from JST
- Suzuken Memorial Foundation
- Uehara Memorial Foundation
- Takeda Science Foundation
- Grants-in-Aid for Scientific Research [15H03120, 24104004, 16K13102, 24651259, 15H00818, 16H00768] Funding Source: KAKEN
Ask authors/readers for more resources
In this work, we developed a red fluorescent turn-off Mg2+ probe with high Mg2+ selectivity. The quenching response to Mg2+ in combination with a green fluorescent turn-on Mg2+ probe enabled a ratiometric imaging of the changes in intracellular Mg2+ concentration. This ratiometric imaging system significantly enhanced the detection sensitivity of intracellular Mg2+ fluctuations in comparison with a conventional ratiometric Mg2+ sensing system, thus leading to a valuable technique for visualizing small change in intracellular Mg2+ concentration.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
