4.5 Article

New Acetophenone Derivatives from Acronychia oligophlebia and Their Anti-inflammatory and Antioxidant Activities

Journal

CHEMISTRY & BIODIVERSITY
Volume 15, Issue 5, Pages -

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201800080

Keywords

Acronychia oligophlebia; acetophenone derivatives; structural elucidation; anti-inflammatory activity; antioxidant activity

Funding

  1. National Natural Science Foundation of China [81473116, 81673319, 81673670]
  2. Science and Technology Planning Project of Guangdong Province [2016B030301004, 2016A030303011]

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Seven new acetophenone derivatives (acroliones A-G, 1-7) and three known ones (8-10) were isolated from the leaves of Acronychia oligophlebia. Their structures were elucidated based on extensive spectroscopic analyses (IR, UV, HR-ESI-MS, 1D- and 2D-NMR), X-ray diffraction and comparison with literature data. The anti-inflammatory and antioxidant activities of all isolates were evaluated.

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