Journal
CHEMICAL REVIEWS
Volume 118, Issue 17, Pages 7931-7985Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.chemrev.7b00731
Keywords
-
Categories
Funding
- H2020 ERC [COG: 648239]
- National Institutes of Health [GM115779, GM120414]
- National Science Foundation [CHE-1566233]
Ask authors/readers for more resources
Deoxy-sugars often play a critical role in modulating the potency of many bioactive natural products. Accordingly, there has been sustained interest in methods for their synthesis over the past several decades. The focus of much of this work has been on developing new glycosylation reactions that permit the mild and selective construction of deoxyglycosides. This Review covers classical approaches to deoxyglycoside synthesis, as well as more recently developed chemistry that aims to control the selectivity of the reaction through rational design of the promoter. Where relevant, the application of this chemistry to natural product synthesis will also be described.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available