Journal
CHEMICAL RECORD
Volume 18, Issue 10, Pages 1517-1529Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/tcr.201800015
Keywords
Hydrogels; Dynamic; Reversible; Supramolecular; Thermogels
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Chemically crosslinked covalent hydrogels form a permanent and often strong network, and have been extensively used so far in drug delivery and tissue engineering. However, it is more difficult to induce dynamic and highly tunable changes in these hydrogels. Noncovalently formed hydrogels show promise as inherently reversible systems with an ability to change in response to dynamic environments, and have garnered strong interest recently. In this Personal Account, we elucidate a few key attractive properties of noncovalent hydrogels and describe recent developments in hydrogels crosslinked using various different noncovalent interactions. These hydrogels offer huge control for modulating material properties and could be more relevant mimics for biological systems.
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