Journal
CHEMICAL PHYSICS LETTERS
Volume 706, Issue -, Pages 741-752Publisher
ELSEVIER
DOI: 10.1016/j.cplett.2018.06.019
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Funding
- NIH [EB003728, CA68485, DK20593, DK58404, DK59637, EY08126]
- NSF Graduate Research Fellowship Program [DGE-1445197]
- CBI Training Grant [NIH T32GM065086-14]
- Vanderbilt Institute of Chemical Biology Summer REU program
- Vanderbilt Ingram Cancer Center [P30 CA68485]
- Vanderbilt Digestive Disease Research Center [DK058404]
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The use of nanometer-sized semiconductor crystals, known as quantum dots, allows us to directly observe individual biomolecular transactions through a fluorescence microscope. Here, we review the evolution of single quantum dot tracking over the past two decades, highlight key biophysical discoveries facilitated by quantum dots, briefly discuss biochemical and optical implementation strategies for a single quantum dot tracking experiment, and report recent accomplishments of our group at the interface of molecular neuroscience and nanoscience. Published by Elsevier B.V.
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