Journal
CHEMICAL COMMUNICATIONS
Volume 54, Issue 16, Pages 1984-1987Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc09803k
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Funding
- Chinese Scholarship Council
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To have a balance between reactivity and selectivity has been a long-standing challenge in multicomponent reactions. In this communication, a carbonylative four-component reaction has been developed. With copper as the catalyst, using ethene including other aliphatic alkenes, alcohols and acetonitrile as the substrates under CO pressure, various desired productswere produced inmoderate to good yields. The obtained products can be applied in the synthesis of delta-valerolactams. Good functional group tolerance and reaction efficiency can be observed here.
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