4.7 Article

Dean flow assisted cell ordering system for lipid profiling in single-cells using mass spectrometry

Journal

CHEMICAL COMMUNICATIONS
Volume 54, Issue 21, Pages 2595-2598

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc09608a

Keywords

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Funding

  1. National Key R&D Program of China [2017YFC0906800]
  2. National Natural Science Foundation of China [214350002, 21727814, 21621003]
  3. China Postdoctoral Science Foundation [2017M620733]

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This study describes a novel Dean flow assisted cell ordering system which is connected to an electrospray ionization-mass spectrometer for the detection of lipids in a single-cell. This platform provides a facile method for direct analysis of label-free lipids in single-cells and significantly improves the efficiency of single-cellmass spectrometry.

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