4.7 Article

Maltodextrin recognition by a macrocyclic synthetic lectin

Journal

CHEMICAL COMMUNICATIONS
Volume 54, Issue 62, Pages 8649-8652

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc05074k

Keywords

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Funding

  1. Engineering and Physical Sciences Research Council [EP/I028501/1]
  2. Engineering and Physical Sciences Research Council (Novartis) [EP/G036764/1]
  3. Netherlands Organisation for Scientific Research (NWO) [723.015.006]
  4. Pakistan Higher Education Commission
  5. BBSRC [BB/F011539/1] Funding Source: UKRI
  6. EPSRC [EP/K03927X/1, EP/L011999/1, EP/I028501/1] Funding Source: UKRI
  7. Engineering and Physical Sciences Research Council [EP/K03927X/1] Funding Source: researchfish

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A monocyclic temple synthetic lectin, with extended electron-rich aromatic surfaces, shows enhanced affinities for carbohydrates in water. The methoxy substituents favour binding to -linked maltodextrins, against the all-equatorial substrates normally favoured by this family of receptors.

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