Journal
CHEMICAL COMMUNICATIONS
Volume 54, Issue 58, Pages 8120-8123Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8cc01400k
Keywords
-
Categories
Funding
- EPSRC [EP/F500416/1, WT 088641/Z/09/Z]
- Medical Research Council [MR/K022733/1]
- Centre of Excellence in Medical Engineering by the Wellcome Trust
- Innovative Medicines Initiative Joint Undertaking from the European Union [115300]
- EFPIA
- Independent Researcher Award (King's College London)
- MRC [MR/K022733/1] Funding Source: UKRI
Ask authors/readers for more resources
A novel (AlF)-F-18 labelled peptide tracer for PET imaging of oxytocin receptor has been accessed through a high radiochemical yield approach. This tracer showed comparable affinity and higher selectivity and stability compared to oxytocin, and was used to demonstrate direct nose-to-brain uptake following intranasal administration, a common yet controversial delivery route for oxytocin-based therapeutics.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available